Searchable abstracts of presentations at key conferences in endocrinology

ea0037oc8.2 | Endocrine tumours | ECE2015

Role of microenvironment on neuroblastoma SK-N-AS SDHB silenced cell metabolism and function

Rapizzi Elena , Fucci Rossella , Giannoni Elisa , Canu Letizia , Richter Susan , Cirri Paolo , Mannelli Massimo

Solid tumours are very complex tissues comprising not only cancer cells, but also non-malignant stromal cells such as endothelial cells, fibroblasts, immune cells and extracellular matrix, forming the so called tumour microenvironment. In the last few years, it has become more and more evident the pivotal role of the tumour microenvironment in modulating cancer progression and metastasis. Tumour microenvironment has thus become a potential therapeutic target. To obtain an expe...